Cloned (Comment) | Organism |
---|---|
gene iolG, expression analysis | Bacillus subtilis |
Protein Variants | Comment | Organism |
---|---|---|
up | iolG expression is induced by myo-inositol, and less by scyllo-inositol | Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-oxo-D-chiro-inositol + NADH + H+ | Bacillus subtilis | - |
D-chiro-inositol + NAD+ | - |
r | |
1-oxo-D-chiro-inositol + NADH + H+ | Bacillus subtilis 168 | - |
D-chiro-inositol + NAD+ | - |
r | |
myo-inositol + NAD+ | Bacillus subtilis | - |
scyllo-inosose + NADH + H+ | - |
r | |
myo-inositol + NAD+ | Bacillus subtilis 168 | - |
scyllo-inosose + NADH + H+ | - |
r | |
pinitol + NADH + H+ | Bacillus subtilis | i.e. 3-O-methyl-D-chiro-inositol. Bacillus subtilis can utilize pinitol as the sole carbon source via the same myo-inositol catabolic pathway | ? | - |
? | |
pinitol + NADH + H+ | Bacillus subtilis 168 | i.e. 3-O-methyl-D-chiro-inositol. Bacillus subtilis can utilize pinitol as the sole carbon source via the same myo-inositol catabolic pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
gene iolG | - |
Bacillus subtilis 168 | - |
gene iolG | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-oxo-D-chiro-inositol + NADH + H+ | - |
Bacillus subtilis | D-chiro-inositol + NAD+ | - |
r | |
1-oxo-D-chiro-inositol + NADH + H+ | - |
Bacillus subtilis 168 | D-chiro-inositol + NAD+ | - |
r | |
additional information | scyllo-inositol is no substrate for the enzyme, thus IolG does not act as a scyllo-inositol dehydrogenase | Bacillus subtilis | ? | - |
? | |
additional information | scyllo-inositol is no substrate for the enzyme, thus IolG does not act as a scyllo-inositol dehydrogenase | Bacillus subtilis 168 | ? | - |
? | |
myo-inositol + NAD+ | - |
Bacillus subtilis | scyllo-inosose + NADH + H+ | - |
r | |
myo-inositol + NAD+ | - |
Bacillus subtilis 168 | scyllo-inosose + NADH + H+ | - |
r | |
pinitol + NADH + H+ | i.e. 3-O-methyl-D-chiro-inositol. Bacillus subtilis can utilize pinitol as the sole carbon source via the same myo-inositol catabolic pathway | Bacillus subtilis | ? | - |
? | |
pinitol + NADH + H+ | i.e. 3-O-methyl-D-chiro-inositol | Bacillus subtilis | ? | - |
? | |
pinitol + NADH + H+ | i.e. 3-O-methyl-D-chiro-inositol. Bacillus subtilis can utilize pinitol as the sole carbon source via the same myo-inositol catabolic pathway | Bacillus subtilis 168 | ? | - |
? | |
pinitol + NADH + H+ | i.e. 3-O-methyl-D-chiro-inositol | Bacillus subtilis 168 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
iolG | - |
Bacillus subtilis |
MI dehydrogenase | - |
Bacillus subtilis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Bacillus subtilis | |
NADH | - |
Bacillus subtilis |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in the myo-inositol catabolic pathway catalyzing the first step, overview | Bacillus subtilis |